MEDICINES / DRUGS

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Isolation process of physalins from plants with antiparasitic activity

 Project 132

Problem to be solved:

  • High toxicity of medicine against Chagas disease and Leishmaniasis
  • Resistance of protozoa strains to currently available medicines 

Proposed Innovation:

  • Isolation of physalin pool of Solanaceae extracts
  • Phytochemical for the treatment of protozoan diseases

Differential:

  • Phytochemical with low toxicity
  • Process with high yield and low operating cost
  • Processfree oftoxic substances
  • National raw material 

Development status:
Prototype 

Intellectual property status:
BRPI9904635-0 (correspondent granted in the U.S.)
BRPI0404635-8

Technology transfer status:
Prospecting partnership 

Coordinator:
Therezinha Coelho Barbosa / Farmanguinhos 

Contact:
Gestec/VPPIS – Phone: 21 3882-9099 / 3882-9120 or portfolio@fiocruz.br