Fluorinated derivatives to treat Tuberculosis

Project 74

Problem to be solved:
• Great public health problem
• High morbidity and mortality
• Resistance of bacterial strains to currently available drugs
• Shortage of new drugs with proven activity

Proposed Innovation:
New products from heterocyclic rings and fluorine atom with anti-tuberculosis activity

Differential:
• Increased bioavailability
• Higher anti-tuberculosis activity

Development status:
Prototype

Intellectual property status:
BRPI0503681-0 (corresponding application filed in China, the United States, Europe, India and granted in South Africa)

Technology transfer status:
Prospecting partnership

Coordinator:
Nubia Boechat Andrade / Farmanguinhos

Contact:
Gestec/VPPIS – Phone: 21 3882-9099 / 3882-9120 or portfolio@fiocruz.br