Development and evaluation of cocrystals of Efavirenz

Project 433

Problem to be solved

Drug with low bioavailability oral

Proposed innovation

New crystal structure of efavirenz with application possibility for adult and pediatric formulations with increased bioavailability and lower dosage

Differential

• Greater dissolution and bioavailability due to the change of the crystalline form of the drug already in use.
• Employed in formulations for adult patients and in specific formulations for pediatric treatment. Employed in formulations for adult patients and in specific formulations for pediatric treatment.

Stage of development

Laboratory prototype

What we want

Transference of technology

Coordinator

Helvécio Vinícius Antunes Rocha / Farmanguinhos

Contact

Gestec/VPPIS – phone: 21 3882 9099/ 3882 9120 or portfolio@fiocruz.br