Fluorinated derivatives to treat Tuberculosis
Project 74
Problem to be solved:
• Great public health problem
• High morbidity and mortality
• Resistance of bacterial strains to currently available drugs
• Shortage of new drugs with proven activity
Proposed Innovation:
New products from heterocyclic rings and fluorine atom with anti-tuberculosis activity
Differential:
• Increased bioavailability
• Higher anti-tuberculosis activity
Development status:
Prototype
Intellectual property status:
BRPI0503681-0 (corresponding application filed in China, the United States, Europe, India and granted in South Africa)
Technology transfer status:
Prospecting partnership
Coordinator:
Nubia Boechat Andrade / Farmanguinhos
Contact:
Gestec/VPPIS – Phone: 21 3882-9099 / 3882-9120 or portfolio@fiocruz.br